Your Partner for Recombinant Antibody Expression in CHO and HEK Cells
For projects where the DNA sequence of the desired antibody is already available, we offer recombinant antibody production using mammalian expression systems that ensure highest product quality and authentic post-translational modifications.
Our Expression Systems
We provide full flexibility in choosing the right expression system – based on your application, quality requirements, and required quantity:
CHO Cells (Chinese Hamster Ovary)
- The most commonly used system for industrial-scale antibody production. CHO cells enable reliable expression of full-length antibodies with human-like glycosylation.
- Ideal for diagnostic applications and preclinical studies. CHO cells also meet all regulatory requirements (e.g., IVDR).
HEK Cells (Human Embryonic Kidney)
- Optimal for transient transfection and high-throughput screening. HEK cells offer rapid expression of recombinant antibodies with excellent scalability.
- Especially suited for early-phase development, assay validation, and functional screening.
Recombinant Antibodies – Flexible, Scalable, Tailored to Your Project
We clone your sequence into a suitable expression system and produce your antibody in the quantity you need.
Depending on your project goal, we offer two proven approaches for recombinant antibody production in our expression systems: Transient Transfection (TT) for fast results and flexible screening, and Stable Transfection (ST) for long-term, consistent antibody production. This method is ideal for:
- Humanized or chimeric antibodies
- Antibody fragments (Fab, scFv)
- Engineered antibodies with optimized characteristics
- Antibodies for specific diagnostic or preclinical applications
Your Advantages with Our Recombinant Antibody Production
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ISO 13485-Certified Processes – ideally suited for in vitro diagnostics and regulatory-sensitive applications.
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Custom Process Development – we select the appropriate expression system (CHO or HEK) and tailor the workflow precisely to your project goals.
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Flexible Batch Sizes – from small test batches to gram-scale production.
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Experience & Expertise – benefit from our long-standing know-how in recombinant production of complex antibody formats.
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Resource-Efficient Execution – optimized workflows and on-demand supply models help save time and costs.
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Fast Turnaround – first results often available within 6–8 weeks thanks to high-performance expression systems.
Your Recombinant Antibody Project – Let’s Talk!
Are you planning to use recombinant antibodies in research, diagnostics, or preclinical development? Then you’ve come to the right place. Contact us today. Our expert team will support you with tailored advice, develop the optimal production strategy, and deliver reliable results – precisely, flexibly, and to the highest quality standards.
Working with hybridoma cell lines or in need of classical monoclonal antibodies? Our monA service also offers tailored solutions for this – from test production to scalable manufacturing.
FAQ – Frequently Asked Questions about Recombinant Antibodies
How long does recombinant antibody production take?
Recombinant antibody production typically takes 8–10 weeks. The exact timeline depends on the chosen expression system (e.g., CHO or HEK cells), transfection strategy (transient or stable), and the required production scale.
What quantities can be produced?
Production quantities using CHO or HEK cells can be flexibly adjusted to meet your specific requirements.
What quality controls do you perform?
Our quality control measures include purity analysis (capillary electrophoresis), aggregate analysis (analytical SEC), protein quantification (A280), and optional endotoxin or functional assays (e.g., ELISA). Additional methods can be integrated on request.
Which certifications do you hold?
Our recombinant antibody production is performed in accordance with ISO 13485 – the internationally recognized quality standard for in vitro diagnostics.
Are your processes IVDR-compliant?
Yes, our production workflows comply with the In Vitro Diagnostic Regulation (IVDR) and are suitable for regulatory-sensitive projects.
In which format are the antibodies delivered?
Recombinant antibodies are typically delivered in liquid buffer formulations (e.g., PBS, pH 7.4). Custom concentrations, alternative buffers, or lyophilized formats are available on request.
Do you offer custom modifications?
Yes, we provide a range of modifications including antibody tags (e.g., His, Strep), conjugations (biotin, enzymes, fluorophores), or targeted mutations – tailored to your specific application.
How is shipping handled?
We ship worldwide using certified logistics partners. Depending on product stability, shipping is done cooled or frozen. Special packaging, such as dry ice, can be provided if needed.
Do you support project planning?
Absolutely. Our team will support you in selecting the optimal expression system, cloning strategy, process development, and QC planning – including all relevant regulatory aspects.
How is the pricing structured?
Pricing depends on the scope and complexity of your project. We provide transparent quotes with detailed breakdowns – from plasmid design to final antibody batch.
Is a confidentiality agreement (NDA) possible?
Yes, of course. Upon request, we will sign a confidentiality agreement (NDA) to ensure the full protection of your project information.