Mammalian Antibody Expression Services (CHO/HEK) for Diagnostic & Research
For projects where the DNA sequence of the desired antibody is already available, we offer ISO 13485-certified Recombinant Antibody Production using mammalian expression systems that ensure IVDR-compliant quality and authentic post-translational modifications.
Our Recombinant Antibody Expression Systems
We provide full flexibility in choosing the right expression system – based on your application, quality requirements, and required quantity:
CHO Cells (Chinese Hamster Ovary)
- The most commonly used system for industrial-scale antibody production. CHO cells enable reliable expression of full-length antibodies with human-like glycosylation.
- Ideal for diagnostic applications and preclinical studies. CHO cells also meet all regulatory requirements (e.g., IVDR).
HEK Cells (Human Embryonic Kidney)
- Optimal for transient transfection and high-throughput screening. HEK cells offer rapid expression of recombinant antibodies with excellent scalability.
- Especially suited for early-phase development, assay validation, and functional screening.
Recombinant Antibodies – Flexible, Scalable, Tailored to Your Project
We clone your sequence into a suitable expression system and produce your antibody in the quantity you need. We understand that time is critical. Our optimized workflows allow for a fast turnaround from gene synthesis to purified antibody, without compromising on quality.
Depending on your project goal, we offer two proven approaches for recombinant antibody production in our expression systems: Transient Transfection Services for fast results and flexible screening, and Stable Cell Line Development for long-term, consistent antibody production. This method is ideal for:
- Humanized or chimeric antibodies
- Antibody fragments (Fab, scFv)
- Engineered antibodies with optimized characteristics
- Antibodies for specific diagnostic or preclinical applications
Your Advantages with Our Recombinant Antibody Expression & Production
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ISO 13485-Certified Processes – ideally suited for IVDR-compliant in vitro diagnostics and regulatory-sensitive applications.
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Custom Process Development – we select the appropriate expression system (CHO or HEK) and tailor the workflow precisely to your project goals.
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Flexible Batch Sizes – from small test batches to gram-scale production.
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Experience & Expertise – benefit from our long-standing know-how in recombinant production of complex antibody formats.
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Resource-Efficient Execution – optimized workflows and on-demand supply models help save time and costs.
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Fast Turnaround – first results often available within 6–8 weeks thanks to high-performance expression systems.
Your Recombinant Antibody Project – Let’s Talk!
Are you planning to use recombinant antibodies in research, diagnostics, or preclinical development? Then you’ve come to the right place. Contact us today. Our expert team will support you with tailored advice, develop the optimal production strategy, and deliver reliable results – precisely, flexibly, and to the highest quality standards.
Working with hybridoma cell lines or in need of classical Monoclonal Antibodies? Our monA service also offers tailored solutions for this – from test production to scalable manufacturing.
FAQ – Frequently Asked Questions about Recombinant Antibody Expression & Production
How long does recombinant antibody production take?
Our gene-to-antibody service typically takes 8–10 weeks. This timeline covers gene synthesis, vector construction, transient transfection (CHO/HEK), and purification. Urgent projects can be accelerated.
What quantities can be produced via recombinant expression?
We offer high-yield expression in CHO and HEK cells. Our scalable process covers everything from small pilot batches (mg scale) to bulk production (gram scale) for preclinical studies.
What quality controls do you perform?
We ensure maximum purity and activity. Standard QC includes CGE-SDS (purity), SEC-HPLC (aggregates), and A280 protein quantification. Optional assays include endotoxin testing (LAL) and functional ELISA.
Is your recombinant antibody manufacturing ISO 13485 certified?
Yes. As a specialized contract manufacturer in Germany, our recombinant antibody production is fully ISO 13485:2016 certified, ensuring the highest standards for IVD and diagnostic products.
Are your processes IVDR-compliant?
Yes, our production workflows are designed to be IVDR-compliant. We provide full documentation and traceability, making our antibodies suitable for regulatory-sensitive diagnostic applications.
In which format are the recombinant antibodies delivered?
Recombinant antibodies are typically delivered in liquid buffer formulations (e.g., PBS pH 7.4). We can provide custom concentrations, specific buffers, or lyophilized formats upon request.
Do you offer antibody engineering and modifications?
Yes, we offer extensive antibody engineering: from isotype switching and Fc-engineering to adding affinity tags (His/Strep) or conjugations with biotin, enzymes, and fluorophores.
How is shipping handled?
We ship worldwide via certified logistics partners. Depending on stability, shipments are cooled or frozen. We also offer dry ice shipping to ensure the integrity of your recombinant proteins.
Do you support project planning and vector design?
Yes, our support starts at the DNA level. We assist with codon optimization, vector design, and cloning strategies to maximize expression yields in the chosen system (HEK/CHO).
How is the pricing structured for recombinant services?
Pricing is based on project scope (e.g., gene synthesis, scale). We provide transparent quotes with a detailed cost breakdown from plasmid design to the final purified antibody batch.
Is a confidentiality agreement (NDA) possible?
Yes, we are happy to sign an NDA to ensure full protection of your sequence data and project information before we start.